Acitretin is a medicine used to manage severe psoriasis. Correcting how outer skin layers develop helps create a smoother, more comfortable surface area.
Acitretin belongs to the retinoid family, synthetic versions of vitamin A that influence how skin cells grow and shed. It is the active compound in medicines such as Soriatane and is used when other treatments have not helped enough.
Retinoids like acitretin slow the overproduction of skin cells, making thick, scaly patches softer and less noticeable. In Australia, acitretin is available only as part of a brand-name product and is taken orally rather than applied to the skin.
Acitretin is most often used for:
These conditions typically affect adults and teenagers who need stronger, systemic therapy.
Acitretin travels through the bloodstream to skin cells that are growing too fast. It adjusts the way skin cells mature, slowing their production and helping them shed more evenly. This reduces the buildup of thick, scaly skin and improves the overall texture and appearance of affected areas.
Acitretin is not suitable for pregnant women or those who could become pregnant, because it can cause serious birth defects. Women of child-bearing potential must use reliable contraception during treatment and for a period after stopping the medication.
People with liver disease, high cholesterol or triglyceride levels, or a history of severe depression should discuss the risks with their healthcare team. Alcohol and vitamin A supplements can increase side-effect chances, so limit these while on acitretin.
For exact interaction details, always check the labeling that comes with your specific medication.
People who are pregnant or could become pregnant, individuals with existing liver disease, and those with high blood-fat levels tend to experience side effects more often. Older adults may also notice stronger skin dryness or joint pain.
Keep acitretin tablets in a cool, dry place away from direct sunlight and moisture, at room temperature and out of reach of children. Follow any specific instructions on the package label. Different Soriatane products can vary in strength and dosing directions.
For detailed usage, dosing, and administration, refer to the specific medication's clinical information.
This article is an educational overview of acitretin, not medical advice. Medicines containing this ingredient (Soriatane) may differ in formulation, strength, and directions. The information provided does not replace professional clinical judgment, and liability for any clinical application is disclaimed. Readers should review their specific medication's labeling and seek guidance from a healthcare professional.
