Formulated for narcolepsy to manage wakefulness and support cognitive alertness.
Mechanism of Action
Modafinil increases wakefulness by increasing extracellular dopamine in the brain through blockade of dopamine reuptake. It may also affect hypothalamic orexin and histamine systems.
Route of Administration
Oral
Onset Time
30–60 minutes
Duration
12–15 hours
Contraindications
Hypersensitivity to modafinil, Recent myocardial infarction, Left ventricular hypertrophy
Severe Adverse Events
Stevens-johnson syndrome, Psychosis, Mania — requires immediate medical attention
Information related to Provigil is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
