Formulated for herpes labialis to manage viral symptoms and support lesion healing.
Mechanism of Action
Topical acyclovir is phosphorylated within virus-infected cells. It inhibits viral DNA polymerase and incorporates into viral DNA to stop synthesis and replication directly at the site of infection.
Route of Administration
Topical
Onset Time
1–2 days
Duration
4–6 hours
Contraindications
Hypersensitivity to acyclovir
Severe Adverse Events
Angioedema, Severe contact dermatitis, Anaphylaxis — requires immediate medical attention
Common Side Effects
Dry skin, Burning, Stinging
Uncommon Side Effects
Itching, Skin flaking, Erythema
Drug Interactions
Alcohol
Pregnancy Safety Warnings
FDA Category B: No evidence of fetal risk. Breastfeeding: Compatible with caution.
Age Restrictions
Safety and efficacy established in pediatric patients 12 years and older.
Information related to Acyclovir Cream 5% is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
