Indicated for hypertension to manage vascular resistance and support blood pressure reduction.
Mechanism of Action
Nifedipine inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle. By blocking calcium channels, it promotes systemic vasodilation and coronary artery relaxation, lowering blood pressure and oxygen demand.
Route of Administration
Oral
Onset Time
20–60 minutes
Duration
8–24 hours
Contraindications
Hypersensitivity to nifedipine, Cardiogenic shock, Concurrent use of rifampin, Recent myocardial infarction
Severe Adverse Events
Severe hypotension, Congestive heart failure, Myocardial infarction — requires immediate medical attention
Information related to Adalat is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.