Intended for glaucoma to manage intraocular pressure and support vision preservation.
Mechanism of Action
Brinzolamide inhibits carbonic anhydrase II in the ciliary processes of the eye. This action decreases the rate of aqueous humor secretion, which effectively lowers the pressure within the eyeball.
Route of Administration
Ophthalmic
Onset Time
2 hours
Duration
12 hours
Contraindications
Hypersensitivity to sulfonamides, Severe renal impairment, Hypersensitivity to brinzolamide
Severe Adverse Events
Corneal edema, Anaphylaxis, Stevens-johnson syndrome — requires immediate medical attention
Common Side Effects
Blurred vision, Bitter taste, Eye discomfort
Uncommon Side Effects
Eye redness, Eyelid crusting, Headache
Drug Interactions
Alcohol, Aspirin, Acetazolamide
Pregnancy Safety Warnings
FDA Category C: Use only if benefit justifies risk. Breastfeeding: Not recommended.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Storage Guidelines
Store at room temperature; shake well before using.
Information related to Azopt is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
