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Depakene
Depakene

2.13
Helps consistent nerve signaling to stabilize electrical activity.
Ingredient
Valproic acid
Category
Neurology
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Valproic acid
Reference Brand
Valproic Acid
Product Origin
Generic Alternative
Reference Manufacturer
AbbVie
Product Form
Capsule, Oral Solution
Regulatory Classification
Rx
Primary Category
Neurology
Product Category
Anticonvulsant
Pharmacological Class
Valproate
Manufacturer Description
Indicated for complex partial seizures to manage neuronal firing and support seizure frequency reduction.
Mechanism of Action
Valproic acid increases the concentration of gamma-aminobutyric acid (GABA) in the brain. It also blocks voltage-gated sodium channels and T-type calcium channels, stabilizing electrical activity across neurons to prevent seizures.
Route of Administration
Oral
Onset Time
1–2 weeks
Duration
9–16 hours
Contraindications
Hepatic disease, Urea cycle disorders, Mitochondrial disorders, Hypersensitivity to valproic acid
Severe Adverse Events
Hepatotoxicity, Pancreatitis, Thrombocytopenia — requires immediate medical attention
Common Side Effects
Nausea, Drowsiness, Tremor
Uncommon Side Effects
Alopecia, Weight gain, Diarrhea
Drug Interactions
Alcohol, Warfarin, Phenytoin, Lamotrigine, Carbamazepine
Pregnancy Safety Warnings
FDA Category D/X: High risk of neural tube defects. Breastfeeding: Excreted in milk; compatible with caution.
Age Restrictions
Safety and efficacy established in pediatric patients for specific seizure types.
Storage Guidelines
Store at room temperature away from moisture.
Related Products
Epilim, Valparin, Depakote
Information related to Depakene is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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