Formulated for pregnancy-related nausea to manage symptomatic distress and support maternal comfort.
Mechanism of Action
The precise mechanism is not fully clear. Doxylamine blocks H1 receptors centrally and peripherally, while Pyridoxine (Vitamin B6) modulates metabolic processes. Together, they provide safe and effective antiemetic action in pregnant women.
Route of Administration
Oral
Onset Time
4–6 hours
Duration
12 hours
Contraindications
Hypersensitivity to any component, Concurrent use of MAO inhibitors
Severe Adverse Events
Anaphylaxis, Severe confusion, Urinary retention — requires immediate medical attention
Common Side Effects
Somnolence, Dry mouth, Headache
Uncommon Side Effects
Dizziness, Nervousness, Diarrhea
Drug Interactions
Alcohol, MAO Inhibitors, Lorazepam, Amitriptyline
Pregnancy Safety Warnings
FDA Category A: Clinically recognized for safe use during pregnancy. Breastfeeding: May be excreted in milk; monitor infant.
Age Restrictions
Indicated for use in pregnant adult women only.
Storage Guidelines
Store at room temperature in original moisture-proof packaging.
Information related to Diclegis is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
