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Esbriet
Esbriet

2.18
Lung function stability stands as the primary indicator for This medication.
Ingredient
Pirfenidone
Category
Respiratory Health
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Pirfenidone
Reference Brand
Pirfenidone
Product Origin
Generic Alternative
Reference Manufacturer
Roche
Product Form
Tablet, Capsule
Regulatory Classification
Rx
Primary Category
COVID-19 Support, Respiratory Health
Product Category
Antifibrotic Agent
Pharmacological Class
Pyridone Derivative
Clinical Indications
Idiopathic pulmonary fibrosis
Manufacturer Description
Utilized for idiopathic pulmonary fibrosis to manage lung scarring and support respiratory maintenance.
Mechanism of Action
Pirfenidone possesses antifibrotic and anti-inflammatory properties. It inhibits the production of TGF-beta and TNF-alpha, which are key cytokines involved in the proliferation of fibroblasts and the formation of scar tissue in the lungs.
Route of Administration
Oral
Onset Time
4–12 weeks
Duration
24 hours
Contraindications
Severe hepatic impairment, Severe renal impairment, Hypersensitivity to pirfenidone
Severe Adverse Events
Hepatotoxicity, Angioedema, Severe sunburn — requires immediate medical attention
Common Side Effects
Nausea, Photosensitivity, Fatigue
Uncommon Side Effects
Abdominal pain, Anorexia, Elevated liver enzymes
Drug Interactions
Alcohol, Fluvoxamine, Tobacco, Ciprofloxacin
Pregnancy Safety Warnings
FDA Category C: Use only if potential benefit outweighs risk. Breastfeeding: Not known if excreted in milk.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Storage Guidelines
Store at room temperature; protect from light.
Related Products
Ofev, Pirfetab
Information related to Esbriet is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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