Utilized for scabies and pruritus to alleviate skin itching and support parasitic clearance.
Mechanism of Action
Crotamiton acts as a scabicide through unknown mechanisms that are lethal to the Sarcoptes scabiei mite. It also provides a direct antipruritic effect by stabilizing mast cells and inhibiting histamine release.
Route of Administration
Topical
Onset Time
1–2 days
Duration
6–10 hours
Contraindications
Hypersensitivity to crotamiton, Acute exudative dermatitis
Severe Adverse Events
Angioedema, Severe skin necrosis, Anaphylaxis — requires immediate medical attention
Common Side Effects
Burning, Skin irritation, Stinging
Uncommon Side Effects
Erythema, Rash, Contact dermatitis
Drug Interactions
Alcohol
Pregnancy Safety Warnings
FDA Category C: Use with caution. Breastfeeding: Use with caution; do not apply to the breast area.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Information related to Eurax is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
