Utilized for allergic rhinitis to alleviate nasal congestion and support respiratory comfort.
Mechanism of Action
When applied nasally, fluticasone binds to glucocorticoid receptors to suppress the migration of inflammatory cells and inhibit the release of cytokines. This multi-level anti-inflammatory action reduces mucosal swelling and allergic symptoms.
Route of Administration
Nasal
Onset Time
1–3 days
Duration
12–24 hours
Contraindications
Hypersensitivity to fluticasone, Recent nasal surgery or trauma
Severe Adverse Events
Nasal septal perforation, Cataracts, Glaucoma — requires immediate medical attention
Common Side Effects
Nasal irritation, Epistaxis, Headache
Uncommon Side Effects
Pharyngitis, Cough, Nausea
Drug Interactions
Alcohol, Ritonavir, Ketoconazole
Pregnancy Safety Warnings
FDA Category C: Use only if clearly needed. Breastfeeding: Compatible with caution.
Age Restrictions
Safety and efficacy established in pediatric patients four years and older.
Information related to Fluticasone is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
