Hydroxyurea
Hydroxyurea

2.17
Cellular activity modulation helps with a sustainable approach to managing certain blood-related concerns.


Ingredient
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Hydroxyurea
Reference Brand
Hydrea
Product Origin
Generic Product
Reference Manufacturer
Bristol-Myers Squibb
Product Form
Capsule
Regulatory Classification
Rx
Primary Category
Oncology Support
Product Category
Antineoplastic
Pharmacological Class
Antimetabolite
Manufacturer Description
Utilized for chronic myeloid leukemia and sickle cell anemia to manage abnormal cell production and support symptom relief.
Mechanism of Action
Hydroxyurea inhibits the enzyme ribonucleotide reductase, which is required for the conversion of ribonucleotides to deoxyribonucleotides. This inhibits DNA synthesis and cellular repair, specifically targeting rapidly dividing cells.
Route of Administration
Oral
Onset Time
1–4 weeks
Duration
Variable
Contraindications
Severe bone marrow suppression, Hypersensitivity to hydroxyurea, Pregnancy
Severe Adverse Events
Myelosuppression, Tumor lysis syndrome, Gangrene — requires immediate medical attention
Common Side Effects
Nausea, Vomiting, Anorexia
Uncommon Side Effects
Rash, Headache, Alopecia
Drug Interactions
Alcohol, Live Vaccines, Didanosine, Stavudine
Pregnancy Safety Warnings
FDA Category D: High risk of fetal toxicity. Breastfeeding: Excreted in milk; not recommended.
Age Restrictions
Safety and efficacy established in pediatric patients nine months and older for sickle cell.
Storage Guidelines
Store at room temperature and protect from light.
Related Products
Hydrea, Droxia, Siklos
Information related to Hydroxyurea is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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