Utilized for hypertension to manage blood pressure levels and support fluid balance.
Mechanism of Action
Indapamide inhibits the reabsorption of sodium in the distal convoluted tubule of the kidney. It also has a direct vascular effect, causing relaxation of arterial smooth muscle and reducing peripheral resistance.
Route of Administration
Oral
Onset Time
1–2 hours
Duration
24 hours
Contraindications
Anuria, Severe renal failure, Hepatic encephalopathy, Hypokalemia
Severe Adverse Events
Severe hypokalemia, Agranulocytosis, Angioedema — requires immediate medical attention
Information related to Indapamide is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.