Utilized for arthritis and acute gout to alleviate joint pain and support anti-inflammatory response.
Mechanism of Action
Indomethacin non-selectively inhibits the enzymes cyclooxygenase-1 and 2. This blocks the synthesis of prostaglandins that mediate systemic inflammation, pain, and fever.
Route of Administration
Oral
Onset Time
30–60 minutes
Duration
6–8 hours
Contraindications
Active peptic ulcer, History of asthma with NSAIDs, Severe renal impairment, Coronary artery bypass graft surgery
Information related to Indomethacin is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
