Formulated for hypothyroidism to manage hormone levels and support metabolic stability.
Mechanism of Action
This synthetic T4 hormone is converted in the body to the active T3 hormone. It binds to thyroid hormone receptors in cell nuclei, regulating gene expression essential for normal growth, development, and metabolism.
Route of Administration
Oral
Onset Time
1–3 weeks
Duration
6–7 days (half-life)
Contraindications
Acute myocardial infarction, Untreated adrenal insufficiency, Thyrotoxicosis, Hypersensitivity to levothyroxine
Severe Adverse Events
Cardiac arrest, Myocardial infarction, Severe hyperthyroidism — requires immediate medical attention
Common Side Effects
Palpitations, Nervousness, Headache
Uncommon Side Effects
Weight loss, Diarrhea, Insomnia
Drug Interactions
Alcohol, Warfarin, Iron Supplements, Calcium Carbonate, Digoxin
Pregnancy Safety Warnings
FDA Category A: Safe for use during pregnancy. Breastfeeding: Compatible; monitor infant.
Age Restrictions
Safety and efficacy established in pediatric patients of all ages.
Information related to Levothyroxine is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
