Utilized for hypertension to manage blood pressure levels and support cardiovascular risk reduction.
Mechanism of Action
The medication selectively inhibits the binding of angiotensin II to the AT1 receptor. This prevents the resulting vasoconstriction and release of aldosterone, leading to peripheral vasodilation and lowered blood pressure.
Route of Administration
Oral
Onset Time
1–2 hours
Duration
24 hours
Contraindications
Pregnancy, Concurrent use of aliskiren in diabetics, Hypersensitivity to losartan
Severe Adverse Events
Renal failure, Angioedema, Fetal toxicity — requires immediate medical attention
Information related to Losartan is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.