Utilized for erectile dysfunction to manage blood flow and target physiological response during stimulation.
Mechanism of Action
Sildenafil inhibits the phosphodiesterase type 5 enzyme. This increases levels of cyclic GMP in the penile tissue, promoting smooth muscle relaxation and enabling blood inflow.
Route of Administration
Oral
Onset Time
30–60 minutes
Duration
4–6 hours
Contraindications
Concurrent use of nitrates, Severe heart disease, Hypersensitivity to sildenafil
Severe Adverse Events
Priapism, Myocardial infarction, Sudden vision loss — requires immediate medical attention
Common Side Effects
Headache, Flushing, Dyspepsia
Uncommon Side Effects
Nasal congestion, Vision changes, Back pain
Drug Interactions
Nitroglycerin, Alcohol, Grapefruit, Ketoconazole
Pregnancy Safety Warnings
FDA Category B: No fetal risk. Breastfeeding: Not applicable.
Information related to Malegra is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
