Utilized for motion sickness and allergic rhinitis to alleviate physical symptoms and support overall comfort.
Mechanism of Action
Promethazine competitively antagonizes histamine at H1 receptors. It also possesses significant anticholinergic, antiemetic, and sedative properties due to its interaction with muscarinic and dopamine receptors.
Route of Administration
Oral
Onset Time
20–60 minutes
Duration
4–12 hours
Contraindications
Pediatric patients under two years of age, Comatose states, Lower respiratory tract symptoms
Information related to Phenergan is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
