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Procoralan
Procoralan

2.28
Action selectively lowers the heart rate by targeting sinus node currents.
Ingredient
Ivabradine
Category
Heart & Blood Pressure
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Ivabradine
Reference Brand
Ivabradine
Product Origin
Generic Alternative
Reference Manufacturer
Servier
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Heart & Blood Pressure
Product Category
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Blocker
Pharmacological Class
HCN Channel Inhibitor
Manufacturer Description
Designed for heart failure and angina to manage heart rate and support cardiovascular efficiency.
Mechanism of Action
Ivabradine selectively inhibits the If 'funny' current in the sinoatrial node. This reduces the pacemaker rate and lowers the heart rate without affecting myocardial contractility or ventricular repolarization.
Route of Administration
Oral
Onset Time
2–4 weeks
Duration
2 hours (half-life)
Contraindications
Resting heart rate below 60 bpm, Cardiogenic shock, Third degree heart block, Sick sinus syndrome, Severe hepatic impairment
Severe Adverse Events
Atrial fibrillation, Severe bradycardia, Angioedema — requires immediate medical attention
Common Side Effects
Luminous phenomena (phospenes), Blurred vision, Headache
Uncommon Side Effects
Bradycardia, Atrioventricular block, Dizziness
Drug Interactions
Alcohol, Grapefruit, Ketoconazole, Clarithromycin, Verapamil, Diltiazem
Pregnancy Safety Warnings
FDA Category D: High risk of fetal toxicity. Breastfeeding: Not recommended.
Age Restrictions
Safety and efficacy established in pediatric patients six months and older for heart failure.
Storage Guidelines
Store below 30°C.
Related Products
Coralan, Ivabrad
Information related to Procoralan is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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