Rheumatrex
Rheumatrex

0.51
The formulation acts on underlying biological pathways to ease joint inflammation and secondary discomfort.


Ingredient
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Methotrexate
Reference Brand
Folitrax
Product Origin
Generic Alternative
Reference Manufacturer
Dava Pharmaceuticals
Product Form
Tablet, Injectable Solution
Regulatory Classification
Rx
Primary Category
Autoimmune Support
Product Category
DMARD
Pharmacological Class
Antifolate
Manufacturer Description
Formulated for rheumatoid arthritis and psoriasis to manage inflammatory symptoms and support disease remission.
Mechanism of Action
Methotrexate irreversibly binds to dihydrofolate reductase, inhibiting the synthesis of thymidylate and purine nucleotides. This stops DNA synthesis and cellular replication in rapidly dividing cells.
Route of Administration
Oral
Onset Time
3–6 weeks
Duration
1 week
Contraindications
Pregnancy, Breastfeeding, Alcoholism, Chronic liver disease, Blood dyscrasias
Severe Adverse Events
Hepatotoxicity, Pulmonary fibrosis, Myelosuppression — requires immediate medical attention
Common Side Effects
Nausea, Headache, Anorexia
Uncommon Side Effects
Stomatitis, Alopecia, Leukopenia
Drug Interactions
Alcohol, NSAIDs, Sulfamethoxazole, Probenecid, Aspirin
Pregnancy Safety Warnings
FDA Category X: Strictly contraindicated. Causes fetal death and malformations. Breastfeeding: Not recommended.
Age Restrictions
Safety and efficacy established in pediatric patients for JIA and oncology.
Storage Guidelines
Store at room temperature away from light.
Related Products
Arava, Trexall, Plaquenil
Information related to Rheumatrex is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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