Utilized for erectile dysfunction to alleviate physiological barriers and support blood flow targeting.
Mechanism of Action
Sildenafil inhibits the PDE5 enzyme, increasing intracellular cGMP levels. This leads to smooth muscle relaxation and increased arterial inflow to the penile tissues.
Route of Administration
Oral
Onset Time
30–60 minutes
Duration
4–6 hours
Contraindications
Concurrent use of nitrates, Hypersensitivity to sildenafil, Severe heart failure
Severe Adverse Events
Priapism, Myocardial infarction, Sudden vision loss — requires immediate medical attention
Common Side Effects
Headache, Flushing, Dyspepsia
Uncommon Side Effects
Nasal congestion, Dizziness, Blurred vision
Drug Interactions
Alcohol, Nitroglycerin, Grapefruit, Ritonavir
Pregnancy Safety Warnings
FDA Category B: No evidence of fetal risk. Breastfeeding: Not applicable.
Information related to Silagra is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
