Intended for erectile dysfunction and premature ejaculation to manage physiological response and support timing regulation.
Mechanism of Action
Avanafil provides rapid PDE5 inhibition to enable blood flow. Dapoxetine inhibits serotonin reuptake to increase synaptic control over the ejaculatory reflex, facilitating managed timing during sexual stimulation.
Route of Administration
Oral
Onset Time
15–30 minutes
Duration
4–6 hours
Contraindications
Concurrent use of nitrates, Concurrent use of MAO inhibitors, Severe heart disease, Severe renal or hepatic impairment
Severe Adverse Events
Priapism, Serotonin syndrome, Syncope — requires immediate medical attention
Common Side Effects
Headache, Flushing, Nausea
Uncommon Side Effects
Dizziness, Insomnia, Nasal congestion
Drug Interactions
Nitroglycerin, Alcohol, MAO Inhibitors, Grapefruit, Ketoconazole
Pregnancy Safety Warnings
FDA Category C: Not applicable. Breastfeeding: Not applicable.
Information related to Top Avana is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.