Utilized for erectile dysfunction and premature ejaculation to manage blood flow and support timing regulation during stimulation.
Mechanism of Action
Sildenafil increases intracellular cGMP to relax penile smooth muscle. Dapoxetine blocks serotonin transporters to increase synaptic serotonin, modulating the ejaculatory threshold in the brain.
Route of Administration
Oral
Onset Time
1–3 hours
Duration
4–6 hours
Contraindications
Concurrent use of nitrates, Concurrent use of MAO inhibitors, Hypersensitivity to sildenafil, Severe liver impairment
Severe Adverse Events
Priapism, Serotonin syndrome, Sudden vision loss — requires immediate medical attention
Common Side Effects
Headache, Flushing, Nausea
Uncommon Side Effects
Dizziness, Insomnia, Nasal congestion
Drug Interactions
Nitroglycerin, MAO Inhibitors, Alcohol, Grapefruit, Ketoconazole
Pregnancy Safety Warnings
FDA Category B/C: Not applicable. Breastfeeding: Not applicable.
Information related to Viagra with Dapoxetine is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.