Formulated for alcohol dependence to support abstinence maintenance and manage neurological balance.
Mechanism of Action
Acamprosate is thought to restore the balance between inhibitory GABA and excitatory glutamate neurotransmission, which is disrupted during chronic alcohol exposure and withdrawal, thereby reducing the urge to drink.
Route of Administration
Oral
Onset Time
1 week
Duration
20–33 hours (half-life)
Contraindications
Severe renal impairment, Hypersensitivity to acamprosate
Severe Adverse Events
Suicidal ideation, Depression, Severe renal failure — requires immediate medical attention
Common Side Effects
Diarrhea, Nausea, Flatulence
Uncommon Side Effects
Insomnia, Anxiety, Itchiness
Drug Interactions
Alcohol
Pregnancy Safety Warnings
FDA Category C: Use with caution. Breastfeeding: Excreted in milk; monitor infant.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Information related to Acamprosate is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
