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Combivir
Combivir

1.6
This combination aids in viral replication inhibition to support immune system resilience.
Ingredients
Lamivudine, Zidovudine
Category
HIV Management
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Lamivudine, Zidovudine
Reference Brand
Duovir
Product Origin
Generic Alternative
Reference Manufacturer
ViiV Healthcare
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
HIV Management
Product Category
Nucleoside Reverse Transcriptase Inhibitor (NRTI)
Pharmacological Class
NRTI Combination
Clinical Indications
Hiv-1 infection
Manufacturer Description
Indicated for hiv-1 infection to target viral replication and support immune system maintenance.
Mechanism of Action
Both components are nucleoside analogues that are intracellularly phosphorylated to active metabolites. These compete with natural substrates for viral reverse transcriptase, leading to DNA chain termination and inhibition of viral replication.
Route of Administration
Oral
Onset Time
2–4 weeks
Duration
12 hours
Contraindications
Hypersensitivity to lamivudine or zidovudine, Low neutrophil count, Low hemoglobin levels
Severe Adverse Events
Lactic acidosis, Hematologic toxicity, Severe hepatomegaly — requires immediate medical attention
Common Side Effects
Headache, Nausea, Insomnia
Uncommon Side Effects
Fatigue, Diarrhea, Anorexia
Drug Interactions
Ganciclovir, Ribavirin, Alcohol, Interferon Alpha, Methadone
Pregnancy Safety Warnings
FDA Category C: Benefit must outweigh risk. Breastfeeding: Not recommended for HIV-positive mothers to prevent transmission.
Age Restrictions
Safety and efficacy established in pediatric patients weighing at least 30 kg.
Storage Guidelines
Store at room temperature in a dry place.
Related Products
Trizivir, Epzicom
Information related to Combivir is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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