VGR Australia VGR Australia

Cyclosporine
Cyclosporine

4.82
Regulating immune system responsiveness provides relief from inflammatory indicators.
Ingredient
Cyclosporine
Category
Autoimmune Support
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Cyclosporine
Reference Brand
Neoral
Product Origin
Generic Product
Reference Manufacturer
Novartis
Product Form
Capsule, Oral Solution, Injectable Solution, Ophthalmic Solution
Regulatory Classification
Rx
Primary Category
Autoimmune Support
Product Category
Calcineurin Inhibitor
Pharmacological Class
Immunosuppressant
Manufacturer Description
Utilized for transplant rejection and psoriasis to manage immune response and support graft or skin stability.
Mechanism of Action
Cyclosporine binds to cyclophilin to form a complex that inhibits calcineurin. This inhibition prevents the dephosphorylation of NFAT, thereby blocking the transcription of IL-2 and subsequent T-lymphocyte activation.
Route of Administration
Oral
Onset Time
1–3 days
Duration
12–24 hours
Contraindications
Hypersensitivity to cyclosporine, Severe renal impairment, Uncontrolled hypertension, Active infection
Severe Adverse Events
Nephrotoxicity, Hepatotoxicity, Lymphoma — requires immediate medical attention
Common Side Effects
Tremor, Hirsutism, Nausea
Uncommon Side Effects
Hypertension, Gingival hyperplasia, Hyperlipidemia
Drug Interactions
Grapefruit, St. John's Wort, Alcohol, NSAIDs, Statins
Pregnancy Safety Warnings
FDA Category C: Benefit must justify risk. Breastfeeding: Excreted in milk; not recommended.
Age Restrictions
Safety and efficacy established in pediatric patients for transplant and specific autoimmune conditions.
Storage Guidelines
Store at room temperature; do not refrigerate oral solution.
Related Products
Neoral, Sandimmun, Prograf
Information related to Cyclosporine is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
Categories
How to access Antidepressant Drugs - Venlafaxine Antidepressant Capsule