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Motegrity
Motegrity

1.56
Regular use stimulates bowel motility and helps with persistent transit delays.
Ingredient
Prucalopride
Category
Digestive Health
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Prucalopride
Reference Brand
Prucalopride
Product Origin
Generic Alternative
Reference Manufacturer
Takeda Pharmaceuticals
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Digestive Health
Product Category
Serotonin 5-HT4 Receptor Agonist
Pharmacological Class
GI Prokinetic
Manufacturer Description
Developed for chronic idiopathic constipation to manage bowel motility and support digestive regularity.
Mechanism of Action
Prucalopride is a high-affinity, selective 5-HT4 receptor agonist. It stimulates colonic mass movements, which provide the primary propulsive force for defecation, thereby improving intestinal transit and stool frequency.
Route of Administration
Oral
Onset Time
24–48 hours
Duration
24 hours
Contraindications
Intestinal perforation, Bowel obstruction, Severe inflammatory bowel disease, Hypersensitivity to prucalopride
Severe Adverse Events
Suicidal ideation, Severe depression, Anaphylaxis — requires immediate medical attention
Common Side Effects
Headache, Nausea, Abdominal pain
Uncommon Side Effects
Diarrhea, Dizziness, Fatigue
Drug Interactions
Alcohol, Erythromycin, Ketoconazole
Pregnancy Safety Warnings
FDA Category C: Use with caution. Breastfeeding: Excreted in milk; monitor infant.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Storage Guidelines
Store at room temperature and protect from moisture.
Related Products
Resotran, Linzess, Amitiza
Information related to Motegrity is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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