VGR Australia VGR Australia

Simvastatin
Simvastatin

0.62
Helps with lower lipid concentrations and relieves arterial lipid deposition.
Ingredient
Simvastatin
Category
Cholesterol Management
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Simvastatin
Reference Brand
Zocor
Product Origin
Generic Product
Reference Manufacturer
Merck Sharp & Dohme
Product Form
Tablet, Oral Suspension
Regulatory Classification
Rx
Primary Category
Cholesterol Management
Product Category
HMG-CoA Reductase Inhibitor
Pharmacological Class
Statin
Manufacturer Description
Utilized for hypercholesterolemia to manage lipid levels and support cardiovascular risk reduction.
Mechanism of Action
Simvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyzes the rate-limiting step in cholesterol biosynthesis. This increases LDL receptor expression on hepatocytes, facilitating the clearance of LDL from the blood.
Route of Administration
Oral
Onset Time
1–2 weeks
Duration
24 hours
Contraindications
Active liver disease, Pregnancy, Breastfeeding, Concurrent use of potent CYP3A4 inhibitors
Severe Adverse Events
Rhabdomyolysis, Immune-mediated necrotizing myopathy, Liver failure — requires immediate medical attention
Common Side Effects
Myalgia, Headache, Dyspepsia
Uncommon Side Effects
Elevated liver enzymes, Insomnia, Abdominal pain
Drug Interactions
Alcohol, Grapefruit, Cyclosporine, Ketoconazole, Gemfibrozil
Pregnancy Safety Warnings
FDA Category X: Strictly contraindicated. Breastfeeding: Contraindicated.
Age Restrictions
Safety and efficacy established in pediatric patients 10 years and older.
Storage Guidelines
Store at room temperature.
Related Products
Zocor, Lipitor, Crestor
Information related to Simvastatin is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
Categories
How to purchase Antidiabetic Drugs Ireland - Buy Glimepiride UK