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Sofosbuvir
Sofosbuvir

29.21
Viral replication processes are addressed to support long-term liver health.
Ingredient
Sofosbuvir
Category
Hepatitis Treatment
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Sofosbuvir
Reference Brand
Sovaldi
Product Origin
Generic Product
Reference Manufacturer
Gilead Sciences
Product Form
Tablet, Oral Pellets
Regulatory Classification
Rx
Primary Category
Antivirals
Product Category
Direct-Acting Antiviral (DAA)
Pharmacological Class
NS5B Polymerase Inhibitor
Clinical Indications
Chronic hepatitis c
Manufacturer Description
Formulated for chronic hepatitis c to target viral replication and support systemic viral clearance.
Mechanism of Action
Sofosbuvir is a nucleotide analogue prodrug. Once metabolized, it inhibits the HCV NS5B RNA-dependent RNA polymerase, which is essential for viral replication, leading to the termination of the viral RNA chain.
Route of Administration
Oral
Onset Time
2–4 weeks
Duration
12–24 weeks (treatment course)
Contraindications
Concurrent use of potent CYP inducers, Hypersensitivity to sofosbuvir
Severe Adverse Events
Severe bradycardia, Hepatitis b virus reactivation, Anaphylaxis — requires immediate medical attention
Common Side Effects
Fatigue, Headache, Nausea
Uncommon Side Effects
Insomnia, Anemia, Pruritus
Drug Interactions
Amiodarone, Rifampin, St. John's Wort, Alcohol, Phenytoin
Pregnancy Safety Warnings
FDA Category B: No evidence of fetal risk. Breastfeeding: Not known if excreted in milk.
Age Restrictions
Safety and efficacy established in pediatric patients three years and older.
Storage Guidelines
Store below 30°C in original container.
Related Products
Harvoni, Epclusa, Vosevi
Information related to Sofosbuvir is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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