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Zestoretic
Zestoretic

0.93
Combined action helps with smoother vessel relaxation while assisting with fluid balance regulation.
Ingredients
Lisinopril, Hydrochlorothiazide
Category
Heart & Blood Pressure
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Lisinopril, Hydrochlorothiazide
Reference Brand
Lisinopril/Hydrochlorothiazide
Product Origin
Generic Alternative
Reference Manufacturer
Merck Sharp & Dohme
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Heart & Blood Pressure
Product Category
ACE Inhibitor, Thiazide Diuretic
Pharmacological Class
ACEI/Thiazide Combination
Clinical Indications
Hypertension
Manufacturer Description
Formulated for hypertension to manage blood pressure levels and support fluid balance.
Mechanism of Action
Lisinopril inhibits ACE, reducing angiotensin II levels to promote vasodilation. Hydrochlorothiazide acts on the distal tubules to inhibit sodium reabsorption, causing diuresis and reducing circulating plasma volume.
Route of Administration
Oral
Onset Time
1–2 hours
Duration
24 hours
Contraindications
History of angioedema, Anuria, Pregnancy, Hypersensitivity to sulfonamides
Severe Adverse Events
Angioedema, Renal failure, Liver failure — requires immediate medical attention
Common Side Effects
Dizziness, Headache, Dry cough
Uncommon Side Effects
Fatigue, Hyperkalemia, Orthostatic hypotension
Drug Interactions
Lithium, NSAIDs, Potassium Supplements, Alcohol, Insulin
Pregnancy Safety Warnings
FDA Category D: High risk of fetal death. Breastfeeding: Use not recommended as both drugs are excreted in milk.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Storage Guidelines
Store at room temperature and protect from light.
Related Products
Prinzipide, Hyzaar
Information related to Zestoretic is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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