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Nexavar
Nexavar

5.87
Substances target key cellular signals to slow abnormal cell growth patterns.
Ingredient
Sorafenib
Category
Oncology Support
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Sorafenib
Reference Brand
Sorafenib
Product Origin
Generic Alternative
Reference Manufacturer
Bayer
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Oncology Support
Product Category
Multikinase Inhibitor
Pharmacological Class
Antineoplastic
Manufacturer Description
Formulated for kidney and liver cancer to target cancer cell pathways and support tumor growth inhibition.
Mechanism of Action
Sorafenib inhibits multiple intracellular and cell-surface kinases, including those involved in tumor cell signaling, angiogenesis, and apoptosis. This dual mechanism prevents tumor cell proliferation and blocks the development of supporting blood vessels.
Route of Administration
Oral
Onset Time
2–4 weeks
Duration
24–48 hours (half-life)
Contraindications
Hypersensitivity to sorafenib, Pregnancy, Concurrent use of carboplatin and paclitaxel in lung cancer
Severe Adverse Events
Hepatotoxicity, Myocardial ischemia, Gastrointestinal perforation — requires immediate medical attention
Common Side Effects
Fatigue, Nausea, Diarrhea
Uncommon Side Effects
Hand-foot skin reaction, Rash, Hypertension
Drug Interactions
Alcohol, Warfarin, Ketoconazole, Rifampin, Docetaxel
Pregnancy Safety Warnings
FDA Category D: High risk of fetal toxicity. Breastfeeding: Not recommended.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Storage Guidelines
Store at room temperature away from moisture.
Related Products
Lenvima, Sutent, Votrient
Information related to Nexavar is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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