Domperidone
Domperidone

0.46
Promoting digestive motility helps with the easing of nausea and abdominal discomfort.


Ingredient
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Domperidone
Reference Brand
Motilium
Product Origin
Generic Product
Reference Manufacturer
Janssen Pharmaceuticals
Product Form
Tablet, Oral Suspension, Suppository
Regulatory Classification
Rx
Primary Category
Digestive Health
Product Category
Antiemetic, Prokinetic
Pharmacological Class
Dopamine D2 Receptor Antagonist
Manufacturer Description
Formulated for nausea and gastroparesis to alleviate digestive symptoms and support gastric motility.
Mechanism of Action
Domperidone selectively antagonizes dopamine D2 receptors in the chemoreceptor trigger zone and the gastrointestinal tract. It increases lower esophageal sphincter pressure and accelerates gastric emptying without crossing the blood-brain barrier significantly.
Route of Administration
Oral
Onset Time
30–60 minutes
Duration
6–8 hours
Contraindications
Prolactin-releasing pituitary tumor, Gastrointestinal hemorrhage, Severe hepatic impairment, Prolonged QT interval
Severe Adverse Events
Qt prolongation, Cardiac arrhythmias, Anaphylaxis — requires immediate medical attention
Common Side Effects
Dry mouth, Headache, Fatigue
Uncommon Side Effects
Galactorrhea, Gynecomastia, Anxiety
Drug Interactions
Alcohol, Ketoconazole, Erythromycin, Amiodarone, Ritonavir
Pregnancy Safety Warnings
FDA Category C: Use only if clearly needed. Breastfeeding: Excreted in milk; compatible with caution.
Age Restrictions
Safety and efficacy established in pediatric patients; use with caution.
Storage Guidelines
Store below 30°C and protect from moisture.
Related Products
Motilium, Maxolon
Information related to Domperidone is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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